Literature summary extracted from

Olsson, M.; Lindahl, T.
Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue (1980), J. Biol. Chem., 255, 10569-10571.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.1.63	additional information	transferase activity methylates itself on removal of the methyl group from the 6-O position of guanine. Modification of a reactive sulfhydryl group can account for the enzyme inactivation accompanying the reaction	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.63	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.63	DNA containing 6-O-methylguanine + [protein]-L-cysteine	transferase activity methylates itself on removal of the methyl group from the 6-O position of guanine	Escherichia coli	DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine	-	?

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Release 2023.1 (January 2023)