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Literature summary extracted from

  • Tomassetti, A.; Driever, P.H.; Pfeifer, G.P.; Drahovsky, D.
    Isolation and characterization of proteins that stimulate the activity of mammalian DNA methyltransferase (1988), Biochim. Biophys. Acta, 951, 201-212.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.1.1.37 stimulating proteins the proteins from murine P815 mastocytoma cells stimulate both de novo and maintenance activity of DNA methyltransferase about 3fold. They enhance the methylation of any natural DNA and of poly[(dI-dC)*(dI-dC)] but inhibit methylation of poly[(dG-dC)*(dG-dC)] Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.37 additional information stimulating proteins from murine P815 mastocytoma cells stimulate both de novo and maintenance activity of DNA methyltransferase about 3fold. They enhance the methylation of any natural DNA and of poly[(dI-dC)*(dI-dC)] but inhibit methylation of poly[(dG-dC)*(dG-dC)] Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.37 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.37
-
Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.37 P-815 cell
-
Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.37 S-adenosyl-L-methionine + DNA
-
Mus musculus S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
-
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