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Literature summary extracted from

  • Sneider, T.W.; Teague, W.M.; Rogachevsky, L.M.
    S-Adenosylmethionine: DNA-cytosine 5-methyltransferase from a Novikoff rat hepatoma cell line (1975), Nucleic Acids Res., 2, 1685-1700.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.37 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.37 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.37 Novikoff hepatoma cell
-
 Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.37 S-adenosyl-L-methionine + DNA
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 Rattus norvegicus S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
-
 ?
2.1.1.37 S-adenosyl-L-methionine + DNA native and heat-denatured DNA from ethionine-treated synchronized Novikoff cells. The native DNA sample is about 3.5 fold better as a methyl acceptor than the heat-denatured sample Rattus norvegicus S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.37 7 7.5
-
 Rattus norvegicus