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Literature summary extracted from

  • Yeo, E.J.; Wagner, C.
    Purification and properties of pancreatic glycine N-methyltransferase (1992), J. Biol. Chem., 267, 24669-24674.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.20 5-Methyltetrahydrofolate hexaglutamate
-
 Rattus norvegicus
2.1.1.20 5-Methyltetrahydrofolate pentaglutamate
-
 Rattus norvegicus
2.1.1.20 5-Methyltetrahydrofolate triglutamate
-
 Rattus norvegicus
2.1.1.20 5-methyltetrahydrofolic acid
-
 Rattus norvegicus
2.1.1.20 5-Methyltetrahydropteroylpentaglutamate
-
 Rattus norvegicus
2.1.1.20 folinic acid
-
 Rattus norvegicus
2.1.1.20 iodoacetate
-
 Rattus norvegicus
2.1.1.20 methotrexate
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.20 34000
-
 x * 34000, SDS-PAGE Rattus norvegicus
2.1.1.20 135000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.20 S-adenosyl-L-methionine + glycine Rattus norvegicus regulates the ratio of S-adenosylmethionine to S-adenosylhomocysteine S-adenosyl-L-homocysteine + sarcosine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.20 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.20
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.20 pancreas
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.20 0.132
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.20 S-adenosyl-L-methionine + glycine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + sarcosine
-
 ?
2.1.1.20 S-adenosyl-L-methionine + glycine regulates the ratio of S-adenosylmethionine to S-adenosylhomocysteine Rattus norvegicus S-adenosyl-L-homocysteine + sarcosine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.1.20 ? x * 34000, SDS-PAGE Rattus norvegicus