Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Heady, J.E.; Kerr, S.J.
    Purification and characterization of glycine N-methyltransferase (1973), J. Biol. Chem., 248, 69-72.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.20 acetate
-
 Oryctolagus cuniculus
2.1.1.20 p-chloromercuribenzoate
-
 Oryctolagus cuniculus
2.1.1.20 S-adenosyl-L-homocysteine
-
 Oryctolagus cuniculus
2.1.1.20 sarcosine weak Oryctolagus cuniculus
2.1.1.20 thioglycolic acid weak Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.20 0.1
-
 S-adenosylmethionine
-
 Oryctolagus cuniculus
2.1.1.20 2.2
-
 glycine
-
 Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.20 123500
-
 sedimentation equilibrium centrifugation Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.20 Oryctolagus cuniculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.1.1.20 glycoprotein 4 residues of sialic acid and 2 residues of hexose per mol of protein Oryctolagus cuniculus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.20
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.20 liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.20 0.7
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.20 S-adenosyl-L-methionine + glycine strict specificity for glycine as methyl acceptor Oryctolagus cuniculus S-adenosyl-L-homocysteine + sarcosine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.1.20 trimer or tetramer 3 or 4 * 27000-33000, nonidentical subunits, SDS-PAGE Oryctolagus cuniculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.1.1.20 37
-
 assay at Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.20 8.4 8.8
-
 Oryctolagus cuniculus