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Literature summary extracted from

  • Makishima, F.; Toyoshima, S.; Osawa, T.
    Partial purification and characterization of phospholipid N-methyltransferases from murine thymocyte microsomes (1985), Arch. Biochem. Biophys., 238, 315-324.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.17 S-adenosylhomocysteine
-
 Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.17 0.02
-
 S-adenosyl-L-methionine
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.17 plasma membrane
-
 Mus musculus 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.1.1.17 Ca2+ 1 mM, increases activity Mus musculus
2.1.1.17 Mg2+ 10 mM, increases activity Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.17 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.17 partial Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.17 thymocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.17 2 S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine the transfer of a methyl group to phosphatidyl-N-methylethanolamine and phosphatidyl-N,N-dimethylethanolamine is catalyzed by a second enzyme Mus musculus 2 S-adenosyl-L-homocysteine + phosphatidylcholine
-
 ?
2.1.1.17 S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine the transfer of a methyl group to phosphatidyl-N-methylethanolamine and phosphatidyl-N,N-dimethylethanolamine is catalyzed by a second enzyme Mus musculus S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine
-
 ?
2.1.1.17 S-adenosyl-L-methionine + phosphatidylethanolamine the transfer of a methyl group to monomethyl-N-phosphatidylcholine and dimethyl-N,N-phosphatidylcholine is catalyzed by a second enzyme Mus musculus S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.17 9
-
-
 Mus musculus