Literature summary extracted from

Safayhi, H.; Anazodo, M.I.; Ammon, H.P.T.
Calmodulin- and calcium-insensitive fatty acid methyltransferase from RINm5F cells. Inhibition by trifluoperazine and W7 (1991), Int. J. Biochem., 23, 769-772.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.1.15	Ca2+	no effect below 0.5 mM	Rattus norvegicus
2.1.1.15	additional information	Ca2+, EGTA and calmodulin have no effect	Rattus norvegicus
2.1.1.15	N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide	W7, very strong inhibition	Rattus norvegicus
2.1.1.15	S-adenosylhomocysteine	-	Rattus norvegicus
2.1.1.15	Trifluoperazine	very strong inhibition	Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.15	S-adenosyl-L-methionine + a fatty acid	Rattus norvegicus	involved in biosynthesis of phosphatidylcholine	S-adenosyl-L-homocysteine + a fatty acid methyl ester	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.15	Rattus norvegicus	-	insulinoma cell line RINm5F	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.15	retina	membrane	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.1.1.15	0.000018	-	-	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.15	S-adenosyl-L-methionine + a fatty acid	-	Rattus norvegicus	S-adenosyl-L-homocysteine + a fatty acid methyl ester	-	?
2.1.1.15	S-adenosyl-L-methionine + a fatty acid	involved in biosynthesis of phosphatidylcholine	Rattus norvegicus	S-adenosyl-L-homocysteine + a fatty acid methyl ester	-	?
2.1.1.15	S-adenosyl-L-methionine + phosphatidylethanolamine	-	Rattus norvegicus	S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine	-	?

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Release 2023.1 (January 2023)