EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.100 | formyl-methionine-leucine-phenylalanine | stimulation of carboxyl methylation of GTP-binding proteins through a substrate-dependent mechanism | Homo sapiens |
EC Number | General Stability | Organism |
---|---|---|
2.1.1.100 | complete loss of activity after exposure to detergent e.g. CHAPS, octyl-beta-glucoside and sodium deoxycholate, activity can be reconstituted by removal of the detergent in the presence of phospholipid | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.100 | 5'-deoxymethylthioadenosine | - |
Homo sapiens | |
2.1.1.100 | S-adenosyl-L-homocysteine | - |
Homo sapiens | |
2.1.1.100 | sinefungin | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.100 | 0.0013 | - |
S-adenosyl-L-methionine | - |
Homo sapiens | |
2.1.1.100 | 0.0014 | - |
N-acetyl-S-geranylgeranyl-L-cysteine | - |
Homo sapiens | |
2.1.1.100 | 0.0116 | - |
N-acetyl-S-(E,E)-farnesyl-L-cysteine | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.100 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.1.100 | blood | - |
Homo sapiens | - |
2.1.1.100 | neutrophil | light membrane fraction | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.100 | S-adenosyl-L-methionine + N-acetyl-S-geranylgeranyl-L-cysteine | - |
Homo sapiens | S-adenosyl-L-homocysteine + N-acetyl-S-geranylgeranyl-L-cysteine methyl ester | - |
? | |
2.1.1.100 | S-adenosylmethionine + N-acetyl-S-(E,E)-farnesyl-L-cysteine | - |
Homo sapiens | S-adenosylhomocysteine + N-acetyl-S-(E,E)-farnesyl-L-cysteine methyl ester | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.100 | 0.00007 | - |
sinefungin | - |
Homo sapiens | |
2.1.1.100 | 0.00157 | - |
S-adenosyl-L-homocysteine | - |
Homo sapiens | |
2.1.1.100 | 3.95 | - |
5'-deoxymethylthioadenosine | - |
Homo sapiens |