Literature summary extracted from

Hovius, R.; Faber, B.; Brigot, B.; Nicolay, K.; de Kruijff, B.
On the mechanism of the mitochondrial decarboxylation of phosphatidylserine (1992), J. Biol. Chem., 267, 16790-16795.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.1.1.65	nitrophene	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
4.1.1.65	membrane	exclusively in the inner mitochondrial membrane	Rattus norvegicus	16020	-
4.1.1.65	membrane	phosphatidylserine flows from the outer membrane to the inner membrane through contact sites between inner and outer membrane to become decarboxylated and the formed phosphatidylethanolamine flows directly back to the outer membrane, without mixing with inner membrane phosphatidylamine	Rattus norvegicus	16020	-
4.1.1.65	mitochondrial inner membrane	exclusively in the inner mitochondrial membrane	Rattus norvegicus	5743	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.65	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.1.1.65	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.65	Phosphatidyl-L-serine	-	Rattus norvegicus	Phosphatidylethanolamine + CO2	-	?

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Release 2023.1 (January 2023)