Any feedback?
Literature summary extracted from
- Phosphatidylserine decarboxylase (1997), Biochim. Biophys. Acta, 1348, 236-244.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.65 | pyruvate | the small subunit contains a pyruvoyl prosthetic group | Escherichia coli |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.1.1.65 | membrane | - |
Mus musculus | 16020 | - |
| 4.1.1.65 | membrane | - |
Escherichia coli | 16020 | - |
| 4.1.1.65 | membrane | inner mitochondrial membrane and Golgi/vacuole membrane | Saccharomyces cerevisiae | 16020 | - |
| 4.1.1.65 | mitochondrial inner membrane | - |
Mus musculus | 5743 | - |
| 4.1.1.65 | mitochondrial inner membrane | inner membrane | Saccharomyces cerevisiae | 5743 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.65 | phosphatidyl-L-serine | Escherichia coli | - |
? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | Mammalia | important enzyme in the synthesis of phosphatidylethanolamine | ? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | Homo sapiens | important enzyme in the synthesis of phosphatidylethanolamine | ? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | Saccharomyces cerevisiae | important enzyme in the synthesis of phosphatidylethanolamine | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.65 | Arabidopsis thaliana | - |
- |
- |
| 4.1.1.65 | Caenorhabditis elegans | - |
- |
- |
| 4.1.1.65 | Escherichia coli | - |
- |
- |
| 4.1.1.65 | Homo sapiens | - |
- |
- |
| 4.1.1.65 | Mammalia | - |
- |
- |
| 4.1.1.65 | Mus musculus | - |
- |
- |
| 4.1.1.65 | Saccharomyces cerevisiae | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 4.1.1.65 | proteolytic modification | the proenzyme is sequentially processed from a size of 46000 Da to 34000 Da. Sequential removal of the mitochondrial targeting and inner membrane sorting sequence, followed by formation of the alpha and beta subunits. The final step in maturation is proposed to be cleavage and concerted prosthetic group attachment to the alpha subunit | Mammalia |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Mammalia | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Mus musculus | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Escherichia coli | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Homo sapiens | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Saccharomyces cerevisiae | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Arabidopsis thaliana | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | Phosphatidyl-L-serine | - |
Caenorhabditis elegans | Phosphatidylethanolamine + CO2 | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | - |
Escherichia coli | ? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | important enzyme in the synthesis of phosphatidylethanolamine | Mammalia | ? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | important enzyme in the synthesis of phosphatidylethanolamine | Homo sapiens | ? | - |
? | |
| 4.1.1.65 | phosphatidyl-L-serine | important enzyme in the synthesis of phosphatidylethanolamine | Saccharomyces cerevisiae | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
