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Literature summary extracted from

  • Freist, W.; von der Haar, F.; Faulhammer, H.; Cramer, F.
    Valyl-tRNA, isoleucyl-tRNA and tyrosyl-tRNA synthetase from baker's yeast. Substrate specificity with regard to ATP analogs and mechanism of the aminoacylation reaction (1976), Eur. J. Biochem., 66, 493-497.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.1 6-Aminomethyladenosine triphosphate
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1.1.5 additional information
-
 additional information Km value of structural analogs of adenosine 5'-triphosphate in the aminoacylation reaction Saccharomyces cerevisiae
6.1.1.9 additional information
-
 additional information Km-values of ATP analogs Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.1 Saccharomyces cerevisiae
-
-
-
6.1.1.5 Saccharomyces cerevisiae
-
-
-
6.1.1.9 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.1 ATP + tyrosine + tRNATyr
-
 Saccharomyces cerevisiae AMP + Tyr-tRNATyr + diphosphate
-
 ?
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
 Saccharomyces cerevisiae AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
6.1.1.5 Formycin 5'-triphosphate + isoleucine + tRNAIle
-
 Saccharomyces cerevisiae ?
-
 ?
6.1.1.5 additional information position 2,6,7,8,9,2' and 3' of ATP are important for catalytic action of isleucyl-tRNA synthetase Saccharomyces cerevisiae ?
-
 ?
6.1.1.5 Tubercidin 5'-triphosphate + isoleucine + tRNAIle
-
 Saccharomyces cerevisiae ?
-
 ?
6.1.1.9 2-chloroadenosine 5'-triphosphate + L-valine + tRNAVal
-
 Saccharomyces cerevisiae 2-chloroadenosine 5'-monophosphate + diphosphate + L-valyl-tRNAVal
-
 ?
6.1.1.9 ATP + L-valine + tRNAVal
-
 Saccharomyces cerevisiae AMP + diphosphate + L-valyl-tRNAVal
-
 ?
6.1.1.9 formycin 5'-triphosphate + L-valine + tRNAVal
-
 Saccharomyces cerevisiae formycin 5'-monophosphate + diphosphate + L-valyl-tRNAVal
-
 ?
6.1.1.9 tubercidin 5'-triphosphate + L-valine + tRNAVal
-
 Saccharomyces cerevisiae tubercidin 5'-monophosphate + diphosphate + L-valyl-tRNAVal
-
 ?