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Literature summary extracted from

  • Holler, E.
    Isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B. Effects of magnesium and spermine on the amino acid activation reaction (1973), Biochemistry, 12, 1142-1149.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.5 spermine catalyzes ATP-diphosphate exchange, no inhibition of specific aminoacylation of tRNAIle Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.5 Escherichia coli
-
B
-
6.1.1.5 Escherichia coli B / ATCC 11303
-
B
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
?
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
Escherichia coli B / ATCC 11303 AMP + diphosphate + L-isoleucyl-tRNAIle
-
?