Literature summary extracted from

Jenal.U.; Rechsteiner, T.; Tan, P.Y.; Buhlmann, E.; Meile, L.; Leisinger, T.
Isoleucyl-tRNA synthetase of Methanobacterium thermoautotrophicum Marburg. Cloning of the gene, nucleotide sequence, and localization of a base change conferring resistance to pseudomonic acid (1991), J. Biol. Chem., 266, 10570-10577.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
6.1.1.5	-	Methanothermobacter thermautotrophicus

Protein Variants

EC Number	Protein Variants	Comment	Organism
6.1.1.5	G590D	pseudomonic-acid resistant mutant MBT10, with a Gly590 to aspartic acid transition	Methanothermobacter thermautotrophicus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.1.1.5	pseudomonic acid	-	Methanothermobacter thermautotrophicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.1.1.5	Methanothermobacter thermautotrophicus	-	-	-
6.1.1.5	Methanothermobacter thermautotrophicus	-	wild-type end pseudomonic-acid resistant mutant MBT10, with a Gly590 to aspartic acid transition	-
6.1.1.5	Methanothermobacter thermautotrophicus Marburg / DSM 2133	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.1.1.5	ATP + L-isoleucine + tRNAIle	-	Methanothermobacter thermautotrophicus	AMP + diphosphate + L-isoleucyl-tRNAIle	-	?
6.1.1.5	ATP + L-isoleucine + tRNAIle	-	Methanothermobacter thermautotrophicus Marburg / DSM 2133	AMP + diphosphate + L-isoleucyl-tRNAIle	-	?

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Release 2023.1 (January 2023)