Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Matuszewska, B.; Borchardt, R.T.
    Guinea pig brain histamine N-methyltransferase: purification and partial characterization (1983), J. Neurochem., 41, 113-118.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.8 S-adenosylhomocysteine
-
 Cavia porcellus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.8 additional information
-
 additional information
-
 Cavia porcellus
2.1.1.8 0.006
-
 S-adenosyl-L-methionine
-
 Cavia porcellus
2.1.1.8 0.014
-
 histamine
-
 Cavia porcellus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.8 29000
-
 gel filtration, SDS-PAGE Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.8 Cavia porcellus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.8
-
 Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.8 brain
-
 Cavia porcellus
-

Storage Stability

EC Number Storage Stability Organism
2.1.1.8 -80°C, 3 months Cavia porcellus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.8 S-adenosyl-L-methionine + histamine
-
 Cavia porcellus S-adenosyl-L-homocysteine + Ntau-methylhistamine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.1.8 monomer 1 * 29000, SDS-PAGE Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.8 7.5
-
 2 optima at pH 7.5 and pH 9.0, brain enzyme Cavia porcellus
2.1.1.8 9
-
 2 optima: pH 7.5 and pH 9.0, brain enzyme Cavia porcellus