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Literature summary extracted from

  • Rhim, H.; Choi, M.U.
    Purification and general characterization of rat brain histamine N-methyltransferase (1989), Hanguk Saenghwahakhoe Chi, 22, 455-461.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.1.1.8 iodoacetamide activation Rattus norvegicus
2.1.1.8 iodoacetic acid activation Rattus norvegicus
2.1.1.8 Succinic anhydride activation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.8 iodoacetamide activation Rattus norvegicus
2.1.1.8 N-ethylmaleimide
-
 Rattus norvegicus
2.1.1.8 p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.8 0.012
-
 histamine
-
 Rattus norvegicus
2.1.1.8 0.04
-
 S-adenosyl-L-methionine
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.8 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.8
-
 Rattus norvegicus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.8 0.004
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.8 S-adenosyl-L-methionine + histamine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + Ntau-methylhistamine
-
 ?