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Literature summary extracted from

  • Di Salvo, M.L.; Delle Fratte, S.; De Biase, D.; Bossa, F.; Schirch, V.
    Purification and characterization of recombinant rabbit cytosolic serine hydroxymethyltransferase (1998), Protein Expr. Purif., 13, 177-183.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.2.1 expression in Escherichia coli Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.2.1 0.02
-
 tetrahydrofolate recombinant enzyme Oryctolagus cuniculus
2.1.2.1 0.15 0.9 L-serine recombinant enzyme Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.2.1 cytoplasm
-
 Oryctolagus cuniculus 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.2.1 L-serine + tetrahydrofolate Oryctolagus cuniculus enzyme is a component of thymidylate cycle glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?
2.1.2.1 L-serine + tetrahydrofolate Oryctolagus cuniculus catalyzes interconversion of serine and glycine glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.1 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.2.1
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.2.1 additional information
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.1 L-serine + tetrahydrofolate
-
 Oryctolagus cuniculus glycine + 5,10-methylenetetrahydrofolate + H2O
-
 r
2.1.2.1 L-serine + tetrahydrofolate enzyme is a component of thymidylate cycle Oryctolagus cuniculus glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?
2.1.2.1 L-serine + tetrahydrofolate catalyzes interconversion of serine and glycine Oryctolagus cuniculus glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.1.2.1 10.5
-
 L-serine
-
 Oryctolagus cuniculus
2.1.2.1 14.2
-
 L-serine recombinant enzyme Oryctolagus cuniculus