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Literature summary extracted from
- Purification, physicochemical and regulatory properties of serine hydroxymethyltransferase from sheep liver (1982), J. Biosci., 4, 31-50.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.1.2.1 | Cibacron blue F3GA | complete inhibition, NAD(H) protects, reversible by tetrahydrofolate | Ovis aries |  |
| 2.1.2.1 | D-cycloserine | - |
Ovis aries | |
| 2.1.2.1 | NAD+ | negative effector | Ovis aries | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.1.2.1 | cytoplasm | - |
Ovis aries | 5737 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 2.1.2.1 | 210000 | - |
gel filtration | Ovis aries |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.1.2.1 | Ovis aries | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 2.1.2.1 | - |
Ovis aries |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.1.2.1 | L-serine + tetrahydrofolate | - |
Ovis aries | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 2.1.2.1 | 60 | - |
- |
Ovis aries |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 2.1.2.1 | 60 | - |
subunit interactions retained | Ovis aries |
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