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Literature summary extracted from

  • Speedie, M.K.; Hornemann, U.; Floss, H.G.
    S-Adenosylmethionine:indolepyruvate 3-methyltransferase (1975), Methods Enzymol., 43, 498-502.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.47 1,10-phenanthroline
-
 Streptomyces griseus
2.1.1.47 2,2'-bipyridyl
-
 Streptomyces griseus
2.1.1.47 additional information no inhibition by EDTA Streptomyces griseus
2.1.1.47 N-ethylmaleimide
-
 Streptomyces griseus
2.1.1.47 p-chloromercuribenzoate
-
 Streptomyces griseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.47 0.0048
-
 Indolepyruvate
-
 Streptomyces griseus
2.1.1.47 0.013
-
 S-adenosyl-L-methionine
-
 Streptomyces griseus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.47 soluble
-
 Streptomyces griseus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.47 55000
-
 gel filtration Streptomyces griseus
2.1.1.47 58500
-
 sucrose density gradient centrifugation Streptomyces griseus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.47 Streptomyces griseus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.47
-
 Streptomyces griseus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.47 0.0083
-
-
 Streptomyces griseus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.47 additional information no substrates are phenylpyruvate, p-hydroxyphenylpyruvate Streptomyces griseus ?
-
 ?
2.1.1.47 S-adenosyl-L-methionine + indolepyruvate
-
 Streptomyces griseus S-adenosyl-L-homocysteine + (S)-beta-methylindolepyruvate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.47 7.5
-
 phosphate buffer Streptomyces griseus
2.1.1.47 7.5 8.5
-
 Streptomyces griseus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.1.1.47 5.5
-
 and below, irreversible inactivation Streptomyces griseus