Literature summary extracted from

Rini, J.; Szumlanski, C.; Guerciolini, R.; Weinshilboum, R.M.
Human liver nicotinamide N-methyltransferase: ion-pairing radiochemical assay, biochemical properties and individual variation (1990), Clin. Chim. Acta, 186, 359-374.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.1.1	additional information	not inhibitory: Ca2+, SKF 525A, 3,4-dimethoxy-5-hydroxybenzoic acid	Homo sapiens
2.1.1.1	N1-methylnicotinamide	-	Homo sapiens
2.1.1.1	S-adenosyl-L-homocysteine	-	Homo sapiens

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.1.1.1	0.00176	-	S-adenosyl-L-methionine	-	Homo sapiens
2.1.1.1	0.347	-	nicotinamide	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.1	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.1	liver	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.1	S-adenosyl-L-methionine + nicotinamide	-	Homo sapiens	S-adenosyl-L-homocysteine + 1-methylnicotinamide	-	?

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Release 2023.1 (January 2023)