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Literature summary extracted from

  • Nishimura, N.; Kakimoto, T.; Chibata, I.
    Mechanism of coenzyme A biosynthesis by Sarcina lutea (1983), J. Ferment. Technol., 61, 95-99.
No PubMed abstract available

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.24 cytosol
-
 Micrococcus luteus 5829
-
2.7.1.33 cytosol
-
 Micrococcus luteus 5829
-
2.7.1.34 cytosol
-
 Micrococcus luteus 5829
-
2.7.7.3 cytosol
-
 Micrococcus luteus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.24 Mg2+ requirement Micrococcus luteus
2.7.1.33 Mg2+
-
 Micrococcus luteus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA Micrococcus luteus
-
 ADP + CoA
-
 ?
2.7.1.34 ATP + pantetheine Micrococcus luteus involved in biosynthesis of CoA ADP + pantetheine 4'-phosphate
-
 ?
2.7.7.3 ATP + pantetheine 4'-phosphate Micrococcus luteus
-
 diphosphate + 3'-dephospho-CoA
-
 ?
4.1.1.36 N-((R)-4-Phosphopantothenoyl)-L-Cys Micrococcus luteus enzyme is involved in coenzyme A biosynthesis ?
-
 ?
6.3.2.5 CTP + (R)-4'-phosphopantothenate + L-Cys Micrococcus luteus Brown´s pathway of CoA synthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.24 Micrococcus luteus
-
-
-
2.7.1.33 Micrococcus luteus
-
-
-
2.7.1.34 Micrococcus luteus
-
-
-
2.7.7.3 Micrococcus luteus
-
-
-
4.1.1.36 Micrococcus luteus
-
-
-
6.3.2.5 Micrococcus luteus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.36 cell culture activity reaches maximal levels in the early stationary phase Micrococcus luteus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.24 additional information
-
-
 Micrococcus luteus
2.7.1.33 additional information
-
-
 Micrococcus luteus
2.7.1.34 additional information
-
-
 Micrococcus luteus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA
-
 Micrococcus luteus ADP + CoA
-
 ?
2.7.1.33 ATP + D-pantothenate
-
 Micrococcus luteus ADP + D-4'-phosphopantothenate
-
 ?
2.7.1.34 ATP + pantetheine
-
 Micrococcus luteus ADP + pantetheine 4'-phosphate
-
 ?
2.7.1.34 ATP + pantetheine involved in biosynthesis of CoA Micrococcus luteus ADP + pantetheine 4'-phosphate
-
 ?
2.7.7.3 ATP + pantetheine 4'-phosphate
-
 Micrococcus luteus diphosphate + 3'-dephospho-CoA
-
 ?
4.1.1.36 N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Micrococcus luteus Pantotheine 4-phosphate + CO2
-
 ?
4.1.1.36 N-((R)-4-Phosphopantothenoyl)-L-Cys enzyme is involved in coenzyme A biosynthesis Micrococcus luteus ?
-
 ?
6.3.2.5 CTP + (R)-4'-phosphopantothenate + L-Cys
-
 Micrococcus luteus (R)-4'-phosphopantothenoyl-L-cysteine + CDP + phosphate
-
 ?
6.3.2.5 CTP + (R)-4'-phosphopantothenate + L-Cys Brown´s pathway of CoA synthesis Micrococcus luteus ?
-
 ?