BRENDA - Enzyme Database

Differences in coenzyme specificity of the N5-methyltetrahydrofolate-homocysteine methyltransferases of various species: implications for corrin binding loci

Beck, W.S.; Thorndike, J.; Biochem. Biophys. Res. Commun. 120, 74-80 (1984)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Escherichia coli
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Homo sapiens
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.13
Escherichia coli
-
-
-
2.1.1.13
Homo sapiens
-
-
-
2.1.1.13
Propionibacterium freudenreichii subsp. shermanii
-
-
-
2.1.1.13
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.1.1.13
-
Escherichia coli
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.13
kidney
-
Homo sapiens
-
2.1.1.13
liver
-
Homo sapiens
-
2.1.1.13
liver
-
Rattus norvegicus
-
2.1.1.13
lymphocyte
-
Homo sapiens
-
2.1.1.13
pancreas
-
Homo sapiens
-
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Escherichia coli
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Homo sapiens
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Rattus norvegicus
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Escherichia coli
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Homo sapiens
2.1.1.13
vitamin B12
-
Propionibacterium freudenreichii subsp. shermanii
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Rattus norvegicus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Escherichia coli
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Homo sapiens
2.1.1.13
cyanocobalamin
supports methyltransferase in extracts of animal tissues and Escherichia coli
Rattus norvegicus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Escherichia coli
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Homo sapiens
2.1.1.13
cobinamide
more active than cyanocobalamin with rat liver enzyme, but inhibitory with E. coli enzyme
Rattus norvegicus
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Escherichia coli
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Homo sapiens
2.1.1.13
vitamin B12
-
Propionibacterium freudenreichii subsp. shermanii
2.1.1.13
vitamin B12
enzyme contains a derivative of vitamin B12 as prosthetic group
Rattus norvegicus
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.1.1.13
-
Escherichia coli
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.13
kidney
-
Homo sapiens
-
2.1.1.13
liver
-
Homo sapiens
-
2.1.1.13
liver
-
Rattus norvegicus
-
2.1.1.13
lymphocyte
-
Homo sapiens
-
2.1.1.13
pancreas
-
Homo sapiens
-