BRENDA - Enzyme Database

5-methyl-5,6,7,8-tetrahydropteroyl oligo-gamma-L-glutamates: synthesis and kinetic studies with methionine synthetase from bovine brain

Coward, J.K.; Chello, P.L.; Cashmore, A.R.; Parameswaran, K.N.; DeAngelis, L.M.; Bertiono, J.R.; Biochemistry 14, 1548-1552 (1975)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.1.1.13
0.0223
-
5-Methyl-5,6,7,8-tetrahydropteroylheptaglutamate
-
Bos taurus
2.1.1.13
0.0244
-
5-methyl-5,6,7,8-tetrahydropteroyltriglutamate
-
Bos taurus
2.1.1.13
0.0277
-
5-Methyl-5,6,7,8-tetrahydropteroylpentaglutamate
-
Bos taurus
2.1.1.13
0.0731
-
5-methyl-5,6,7,8-tetrahydropteroylmonoglutamate
-
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.13
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.13
brain
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.13
5-methyl-5,6,7,8-tetrahydropteroylheptaglutamate + homocysteine
-
441194
Bos taurus
?
-
-
-
?
2.1.1.13
5-methyl-5,6,7,8-tetrahydropteroylpentaglutamate + L-homocysteine
-
441194
Bos taurus
?
-
-
-
?
2.1.1.13
N5-methyltetrahydrofolate + L-homocysteine
-
441194
Bos taurus
tetrahydrofolate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylheptaglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylheptaglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylmonoglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylmonoglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylpentaglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylpentaglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroyltriglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroyltriglutamate + L-methionine
-
-
-
?
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.1.1.13
0.0223
-
5-Methyl-5,6,7,8-tetrahydropteroylheptaglutamate
-
Bos taurus
2.1.1.13
0.0244
-
5-methyl-5,6,7,8-tetrahydropteroyltriglutamate
-
Bos taurus
2.1.1.13
0.0277
-
5-Methyl-5,6,7,8-tetrahydropteroylpentaglutamate
-
Bos taurus
2.1.1.13
0.0731
-
5-methyl-5,6,7,8-tetrahydropteroylmonoglutamate
-
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.13
brain
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.13
5-methyl-5,6,7,8-tetrahydropteroylheptaglutamate + homocysteine
-
441194
Bos taurus
?
-
-
-
?
2.1.1.13
5-methyl-5,6,7,8-tetrahydropteroylpentaglutamate + L-homocysteine
-
441194
Bos taurus
?
-
-
-
?
2.1.1.13
N5-methyltetrahydrofolate + L-homocysteine
-
441194
Bos taurus
tetrahydrofolate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylheptaglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylheptaglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylmonoglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylmonoglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroylpentaglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroylpentaglutamate + L-methionine
-
-
-
?
2.1.1.13
N5-methyltetrahydropteroyltriglutamate + L-homocysteine
-
441194
Bos taurus
tetrahydropteroyltriglutamate + L-methionine
-
-
-
?