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Literature summary extracted from

  • Soon, C.Y.; Sheperd, M.G.; Sullivan, P.A.
    Inactivation and modification of lactate oxidase with fluorodinitrobenzene (1978), Biochem. J., 173, 255-262.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.12.4 1-Fluoro-2,4-dinitrobenzene after 2 h at 2 mM, complete inactivation by dinitrophenylation of 2 mol of histidine residues per mol of enzyme-bound FMN, competitive inhibitors such as phosphate, nitrate and alpha-hydroxymalonate decrease the rate of inactivation Mycolicibacterium smegmatis
1.13.12.4 2-Methyllactate competitive inhibitor Mycolicibacterium smegmatis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.12.4 (S)-lactate + O2 Mycolicibacterium smegmatis
-
acetate + CO2 + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.13.12.4 Mycolicibacterium smegmatis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.12.4 (S)-lactate + O2
-
Mycolicibacterium smegmatis acetate + CO2 + H2O
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.13.12.4 FMN
-
Mycolicibacterium smegmatis

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.13.12.4 4
-
2-methyl-lactate
-
Mycolicibacterium smegmatis