BRENDA - Enzyme Database show

Nitrogenases without molybdenum

Pau, R.N.; Trends Biochem. Sci. 14, 183-186 (1989)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.18.6.1
Vanadium
contains 3 classes of nitrogenase, the second contains V, the third is encoded by a separate set of genes and is inhibited by V and Mo
Azotobacter vinelandii
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.18.6.1
Molybdenum
also possesses Mo-independent nitrogenases: one vanadium containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter vinelandii
1.18.6.1
Molybdenum
-
Azotobacter chroococcum
1.18.6.1
additional information
-
Azotobacter chroococcum
1.18.6.1
additional information
-
Azotobacter vinelandii
1.18.6.1
Vanadium
possesses 2 molybdenum-independent nitrogenases: one vanadium-containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter chroococcum
1.18.6.1
Vanadium
possesses 2 molybdenum-independent nitrogenases: one vanadium-containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter vinelandii
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
Azotobacter vinelandii
-
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
Azotobacter chroococcum
-
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.18.6.1
Azotobacter chroococcum
-
-
-
1.18.6.1
Azotobacter vinelandii
-
contains 3 classes of nitrogenase, the second contains V, the third is encoded by a separate set of genes and is lacking V and Mo and is inhibited by V and Mo
-
Reaction
EC Number
Reaction
Commentary
Organism
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
enzyme is composed of 2 metalloproteins: component I MoFe protein and component II Fe protein; schematic mechanism; structure of V-containing enzyme form
Azotobacter vinelandii
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
enzyme is composed of 2 metalloproteins: component I MoFe protein and component II Fe protein; schematic mechanism
Azotobacter chroococcum
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.18.6.1
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP
-
440150
Azotobacter vinelandii
6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter vinelandii
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter vinelandii
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
440150
Azotobacter vinelandii
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter chroococcum
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter chroococcum
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
440150
Azotobacter chroococcum
?
1.18.6.1
dithionite + H+ + N2 + ATP
in vitro substrate
440150
Azotobacter vinelandii
?
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.18.6.1
Vanadium
contains 3 classes of nitrogenase, the second contains V, the third is encoded by a separate set of genes and is inhibited by V and Mo
Azotobacter vinelandii
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.18.6.1
Molybdenum
also possesses Mo-independent nitrogenases: one vanadium containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter vinelandii
1.18.6.1
Molybdenum
-
Azotobacter chroococcum
1.18.6.1
additional information
-
Azotobacter chroococcum
1.18.6.1
additional information
-
Azotobacter vinelandii
1.18.6.1
Vanadium
possesses 2 molybdenum-independent nitrogenases: one vanadium-containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter chroococcum
1.18.6.1
Vanadium
possesses 2 molybdenum-independent nitrogenases: one vanadium-containing nitrogenase and another lacking both molybdenum and vanadium
Azotobacter vinelandii
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
Azotobacter vinelandii
-
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
Azotobacter chroococcum
-
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.18.6.1
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP
-
440150
Azotobacter vinelandii
6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter vinelandii
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter vinelandii
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
440150
Azotobacter vinelandii
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter chroococcum
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
-
-
?
1.18.6.1
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O
-
440150
Azotobacter chroococcum
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
-
440150
Azotobacter chroococcum
?
1.18.6.1
dithionite + H+ + N2 + ATP
in vitro substrate
440150
Azotobacter vinelandii
?
-
-
-
?