EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.18.6.1 | O2 | complete reversible inhibition, reversibility decreases by increasing the time of exposure to O2 | Klebsiella pneumoniae | |
1.19.6.1 | O2 | complete reversible inhibition, reversibility decreases by increasing the time of exposure to O2 | Klebsiella pneumoniae |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.19.6.1 | Mg2+ | required for ATP hydrolysis | Klebsiella pneumoniae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.18.6.1 | 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O | Klebsiella pneumoniae | - |
8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate | - |
? | |
1.19.6.1 | 6 reduced flavodoxin + N2 + 6 H2O + 6 ATP | Klebsiella pneumoniae | anaerobic conditions are required by the enzyme | 6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.18.6.1 | Klebsiella pneumoniae | - |
- |
- |
1.19.6.1 | Klebsiella pneumoniae | - |
- |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
1.18.6.1 | complete reversible inhibition by O2, reversibility decreases by increasing the time of exposure to O2, after 20 min 60% reversibility of the inhibition remains | Klebsiella pneumoniae |
1.19.6.1 | complete reversible inhibition by O2, reversibility decreases by increasing the time of exposure to O2, after 20 min 60% reversibility of the inhibition remains | Klebsiella pneumoniae |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.18.6.1 | 4 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 4 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate | enzyme is composed of 2 metalloproteins: component I MoFe protein and component II Fe protein | Klebsiella pneumoniae |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.18.6.1 | 0.027 | - |
reductant dithionite, whole cell assay | Klebsiella pneumoniae |
1.19.6.1 | 0.027 | - |
reductant dithionite | Klebsiella pneumoniae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.18.6.1 | 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O | - |
Klebsiella pneumoniae | 8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate | - |
? | |
1.18.6.1 | dithionite + H+ + N2 + ATP | in vitro substrate | Klebsiella pneumoniae | ? | - |
? | |
1.19.6.1 | 6 reduced flavodoxin + N2 + 6 H2O + 6 ATP | - |
Klebsiella pneumoniae | 6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate | - |
? | |
1.19.6.1 | 6 reduced flavodoxin + N2 + 6 H2O + 6 ATP | anaerobic conditions are required by the enzyme | Klebsiella pneumoniae | 6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate | - |
? | |
1.19.6.1 | dithionite + H+ + N2 + ATP | - |
Klebsiella pneumoniae | ? | - |
? |