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Literature summary extracted from

  • Banko, G.; Demain, A.L.; Wolfe, S.
    delta-(L-alpha-Aminoadipyl)-L-cysteinyl-D-valine synthetase (ACV synthetase): a multifunctional enzyme with broad substrate specificity for the synthesis of penicillin and cephalosporin precursors (1987), J. Am. Chem. Soc., 109, 2858-2860.
No PubMed abstract available

General Stability

EC Number General Stability Organism
6.3.2.26 glycerol stabilizes enzyme activity Acremonium chrysogenum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.2.26 0.026
-
 L-cysteine
-
 Acremonium chrysogenum
6.3.2.26 0.17
-
 L-aminoadipate
-
 Acremonium chrysogenum
6.3.2.26 0.34
-
 L-valine
-
 Acremonium chrysogenum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.26 Mg2+ optimal concentration: 10 mM Acremonium chrysogenum
6.3.2.26 Mn2+ optimal concentration: 10 mM Acremonium chrysogenum

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.26 Acremonium chrysogenum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.26 L-2-aminoadipate + L-cysteine + L-valine + ATP
-
 Acremonium chrysogenum N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + AMP + diphosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.3.2.26 25
-
 assay at Acremonium chrysogenum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3.2.26 7.5
-
 assay at Acremonium chrysogenum

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.2.26 ATP
-
 Acremonium chrysogenum