Literature summary extracted from

Ravn, M.M.; Coates, R.M.; Flory, J.E.; Peters, R.J.; Croteau, R.
Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (-)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis (2000), Org. Lett., 2, 573-576.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.2.3.18	expression in Escherichia coli	Abies grandis
5.5.1.12	expression in Escherichia coli	Abies grandis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.2.3.18	(+)-copalyl-diphosphate	Abies grandis	-	(-)-abietadiene + diphosphate	-	?
5.5.1.12	geranylgeranyl diphosphate	Abies grandis	-	(+)-copalyl diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.18	Abies grandis	-	-	-
5.5.1.12	Abies grandis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.18	(+)-copalyl-diphosphate	-	Abies grandis	(-)-abietadiene + diphosphate	-	?
4.2.3.18	8alpha-hydroxy-17-nor copalyl diphosphate	-	Abies grandis	17-normanoyl oxide + diphosphate	-	?
5.5.1.12	geranylgeranyl diphosphate	-	Abies grandis	(+)-copalyl diphosphate	-	?

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Release 2023.1 (January 2023)