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Literature summary extracted from

  • Schaegger, H.; Brandt, U.; Gencic, S.; von Jagow, G.
    Ubiquinol-cytochrome-c reductase from human and bovine mitochondria (1995), Methods Enzymol., 260, 82-96.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.1.1.8 dodecyl maltoside
-
 Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.8 hydroxyapatite
-
 Bos taurus
7.1.1.8 Stigmatellin
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.8 membrane
-
 Saccharomyces cerevisiae 16020
-
7.1.1.8 membrane membrane-bound Homo sapiens 16020
-
7.1.1.8 membrane membrane-bound Bos taurus 16020
-
7.1.1.8 mitochondrion
-
 Saccharomyces cerevisiae 5739
-
7.1.1.8 mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.1.1.8 6400
-
 ISP-associated protein, SDS-PAGE Bos taurus
7.1.1.8 6519
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 7200
-
 cytochrome c1-associated protein, SDS-PAGE Bos taurus
7.1.1.8 7326
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 7955
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 8000
-
-
 Bos taurus
7.1.1.8 8000
-
 subunit IX, SDS-PAGE Homo sapiens
7.1.1.8 8053
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 9174
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 9261
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 9588
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 13345
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 13380
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 21608
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 21630
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 27285
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 27350
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 42588
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 42727
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 46520
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 46808
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 47000
-
 core protein I, SDS-PAGE Bos taurus
7.1.1.8 48960
-
 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 49200
-
 core protein I, amino acid sequence Bos taurus
7.1.1.8 49209
-
 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus
7.1.1.8 241100
-
 total mass of protein moiety Bos taurus
7.1.1.8 243300
-
 complete enzyme monomer, amino acid composition Bos taurus
7.1.1.8 500000
-
 analytical ultracentrifugation Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.8 Bos taurus
-
-
-
7.1.1.8 Homo sapiens
-
 human
-
7.1.1.8 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.8
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.1.1.8 heart
-
 Homo sapiens
-
7.1.1.8 heart
-
 Bos taurus
-
7.1.1.8 liver
-
 Homo sapiens
-
7.1.1.8 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Homo sapiens ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Saccharomyces cerevisiae ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Bos taurus ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?

Subunits

EC Number Subunits Comment Organism
7.1.1.8 dimer
-
 Bos taurus
7.1.1.8 octamer
-
 Saccharomyces cerevisiae
7.1.1.8 octamer
-
 Bos taurus
7.1.1.8 octamer 1 * 48960 + 1 * 46808 + 1 * 42727 + 1 * 27350 + 1 * 21630 + 1 * 13380 + 1 * 9261 + 1 * 8053, calculated from the amino acid sequence of the mature protein Homo sapiens
7.1.1.8 undecamer 1 * 49209 + 1 * 46520 + 1 * 42588 + 1 * 27285 + 1 * 21608 + 1 * 13345 + 1 * 9588 + 1 * 9174 + 1 * 7955 + 1 * 7326 + 1 * 6519, core protein I, core protein II, cytochrome b, cytochrome c1, iron-sulfur protein, cytochrome b-associated protein, core associated protein, hinge protein, ISP targeting peptide, cytochrome c1-associated protein, ISP-associated protein, calculated from amino acid sequence of the mature protein Bos taurus