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Literature summary extracted from

  • Gardas, A.; Lewartowska, A.; Sutton, B.J.; Pasieka, Z.; McGregor, M.; Banga, J.P.
    Human thyroid peroxidase (TPO) isoforms, TPO-1 and TPO-2: Analysis of protein expression in Graves' thyroid tissue (1997), J. Clin. Endocrinol. Metab., 82, 3752-3756.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.11.1.8 microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.8 100000
-
 SDS-PAGE, isoform 2 Homo sapiens
1.11.1.8 105000
-
 SDS-PAGE, isoform 1 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.8 iodide + H2O2 Homo sapiens biosynthesis of thyroid hormones iodine + H2O
-
 ?
1.11.1.8 iodide + H2O2 Homo sapiens autoantigenin autoimmune thyroid disease iodine + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.8 Homo sapiens
-
 two isoforms found
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.1.8
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.8 thyroid gland
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
1.11.1.8 -70°C, 50 mM Tris-HCl, 0.15 M NaCl, pH 8.5, 0.1% deoxycholate Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.8 iodide + H2O2
-
 Homo sapiens iodine + H2O
-
 ?
1.11.1.8 iodide + H2O2 biosynthesis of thyroid hormones Homo sapiens iodine + H2O
-
 ?
1.11.1.8 iodide + H2O2 autoantigenin autoimmune thyroid disease Homo sapiens iodine + H2O
-
 ?