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Literature summary extracted from
- The bacterial oxidation of indole (1968), Biochim. Biophys. Acta, 158, 70-78.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.11.23 | 2,3-Dimercaptopropanol | 47% inhibition at 1 mM, 59% inhibition at 5 mM | uncultured bacterium |  |
| 1.13.11.23 | ascorbic acid | 30% inhibition at 1 mM | uncultured bacterium | |
| 1.13.11.23 | catechol | 45% inhibition at 1 mM | uncultured bacterium | |
| 1.13.11.23 | o-phenanthroline | 46% inhibition at 1 mM | uncultured bacterium | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.23 | 2,3-dihydroxyindole + O2 | uncultured bacterium | - |
anthranilate + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.11.23 | uncultured bacterium | - |
an aerobic Gram-positive coccus isolated from soil, grown on indole | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.13.11.23 | using sonic extracts, protamine sulfate treatment, ammonium sulfate fractionation, treatment with alumina C-gamma gel and column chromatography on DEAE-cellulose | uncultured bacterium |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.13.11.23 | 13 | - |
- |
uncultured bacterium |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.13.11.23 | -20°C, pH 7, 1 month | uncultured bacterium |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.23 | 2,3-dihydroxyindole + O2 | - |
uncultured bacterium | anthranilate + CO2 | - |
? | |
| 1.13.11.23 | 2,3-dihydroxyindole + O2 | with dihydroxyindole as the intermediate | uncultured bacterium | anthranilate + CO2 | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.13.11.23 | 8 | - |
- |
uncultured bacterium |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.13.11.23 | 6 | - |
unstable below | uncultured bacterium |
| 1.13.11.23 | 7 | 9 | stable | uncultured bacterium |
| 1.13.11.23 | 10 | - |
unstable above | uncultured bacterium |
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Release 2023.1 (January 2023)
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