Literature summary extracted from

Mirzoeva, O.K.; Sud'ina, G.F.; Pushkareva, M.A.; Varfolomeev, S.D.
Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids (1995), FEBS Lett., 377, 306-308.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.34	5-hydroperoxy-6,8,11,14-eicosatetraenoic acid	-	Hordeum vulgare
1.13.11.34	arachidonic acid	competitive inhibitor of linoleic acid oxidation	Hordeum vulgare

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.13.11.34	0.022	-	arachidonic acid	-	Hordeum vulgare

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.34	Hordeum vulgare	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.34	caryopsis	-	Hordeum vulgare	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.34	arachidonate + O2	i.e. 5,8,11,14-eicosatetraenoic acid	Hordeum vulgare	(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate	-	?
1.13.11.34	linoleic acid + O2	-	Hordeum vulgare	9-hydroperoxyoctadecadienoic acid	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.13.11.34	0.0005	-	5-hydroperoxy-6,8,11,14-eicosatetraenoic acid	-	Hordeum vulgare
1.13.11.34	0.02	-	arachidonic acid	-	Hordeum vulgare

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Release 2023.1 (January 2023)