EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.1 | catalase | - |
Rattus norvegicus | |
1.14.11.1 | Cs+ | increase of activity | Rattus norvegicus | |
1.14.11.1 | GSH/GSH-peroxidase | increase of activity, more efficient in assay and during preincubation than catalase, protects the enzyme from increasing phosphate concentrations | Rattus norvegicus | |
1.14.11.1 | K+ | efficient coupling of decarboxylation and hydroxylation, stimulation | Rattus norvegicus | |
1.14.11.1 | NH4+ | increase of activity | Rattus norvegicus | |
1.14.11.1 | Rb+ | increase of activity | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.1 | 3-Bromo-2-oxoglutarate | noncompetitive inhibition, 2-oxoglutarate as variable substrate | Rattus norvegicus | |
1.14.11.1 | 3-glutathione-2-oxoglutarate | noncompetitive to 2-oxoglutarate | Rattus norvegicus | |
1.14.11.1 | DL-carnitine | - |
Rattus norvegicus | |
1.14.11.1 | phosphate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.11.1 | 0.029 | - |
gamma-butyrobetaine | - |
Rattus norvegicus | |
1.14.11.1 | 0.052 | - |
L-carnitine | - |
Rattus norvegicus | |
1.14.11.1 | 0.47 | - |
D-carnitine | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.11.1 | cytoplasm | - |
Rattus norvegicus | 5737 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.1 | Fe2+ | requirement | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.1 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.11.1 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.1 | 4-trimethylammoniobutanoate + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2 | - |
? | |
1.14.11.1 | D-carnitine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 3-carboxy-N,N,N-trimethyl-2-oxopropan-1-aminium + succinate + CO2 | - |
r | |
1.14.11.1 | L-carnitine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 3-carboxy-N,N,N-trimethyl-2-oxopropan-1-aminium + succinate + CO2 | - |
r |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.11.1 | 37 | - |
assay at | Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.1 | ascorbate | - |
Rattus norvegicus |