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Literature summary extracted from

  • Punekar, N.S.; Wehbie, R.S.; Lardy, H.A.
    gamma-Butyrobetaine hydroxylase and the protective role of glutathione peroxidase (1987), J. Biol. Chem., 262, 6720-6724.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.11.1 catalase protection from inactivation Rattus norvegicus
1.14.11.1 GSH/GSH-peroxidase increase of activity, more efficient in assay and during preincubation than catalase, protects the enzyme from increasing phosphate concentrations Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.11.1 cytoplasm
-
 Rattus norvegicus 5737
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.11.1 Fe2+ requirement Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.1 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.11.1
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.1 blood
-
 Rattus norvegicus
-
1.14.11.1 liver
-
 Rattus norvegicus
-
1.14.11.1 skeletal muscle
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.11.1 0.0274
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.1 4-trimethylammoniobutanoate + 2-oxoglutarate + O2
-
 Rattus norvegicus 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.14.11.1 37
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.11.1 ascorbate
-
 Rattus norvegicus