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Literature summary extracted from
- Lysyl hydroxylase, a collagen processing enzyme, exemplifies a novel class of luminally-oriented peripheral membrane proteins in the endoplasmic reticulum (1994), J. Biol. Chem., 269, 30524-30529.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.11.4 | endoplasmic reticulum | lumen | Homo sapiens | 5783 | - |
| 1.14.11.4 | membrane | enzyme binds to membrane via weak electrostatic interactions | Homo sapiens | 16020 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.11.4 | 150000 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.11.4 | collagen + 2-oxoglutarate + O2 | Homo sapiens | enzyme required during collagen biosynthesis | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.11.4 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.11.4 | embryo | - |
Homo sapiens | - |
| 1.14.11.4 | skin | fibroblasts | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.11.4 | collagen + 2-oxoglutarate + O2 | enzyme required during collagen biosynthesis | Homo sapiens | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? | |
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Release 2023.1 (January 2023)
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