Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lai, M.T.; Wu, W.; Stubbe, J.
    Characterization of a novel, stable norcaradiene adduct resulting from the inactivation of thymine hydroxylase by 5-ethynyluracil (1995), J. Am. Chem. Soc., 117, 5023-5030.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.11.6 5-Ethynyluracil binds covalently to a phenylalanine residue of the enzyme Rhodotorula glutinis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.11.6 Fe2+
-
 Rhodotorula glutinis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.6 5-formyluracil + 2-oxoglutarate + O2 Rhodotorula glutinis
-
 5-carboxyuracil + succinate + CO2
-
 ?
1.14.11.6 5-hydroxymethyluracil + 2-oxoglutarate + O2 Rhodotorula glutinis
-
 5-formyluracil + succinate + CO2 5-formyluracil reacts subsequently to 5-carboxyuracil ?
1.14.11.6 thymine + 2-oxoglutarate + O2 Rhodotorula glutinis
-
 5-hydroxymethyluracil + succinate + CO2 5-hydroxymethyluracil reacts subsequently to 5-formyluracil ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.6 Rhodotorula glutinis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.6 5-ethynyluracil + 2-oxoglutarate + O2 + H2O
-
 Rhodotorula glutinis 5-(carboxymethyl)uracil + succinate + CO2
-
 ?
1.14.11.6 5-formyluracil + 2-oxoglutarate + O2
-
 Rhodotorula glutinis 5-carboxyuracil + succinate + CO2
-
 ?
1.14.11.6 5-formyluracil + 2-oxoglutarate + O2 5-formyluracil reacts subsequently to 5-carboxyuracil Rhodotorula glutinis 5-carboxyuracil + succinate + CO2
-
 ?
1.14.11.6 5-hydroxymethyluracil + 2-oxoglutarate + O2
-
 Rhodotorula glutinis 5-formyluracil + succinate + CO2
-
 ?
1.14.11.6 5-hydroxymethyluracil + 2-oxoglutarate + O2
-
 Rhodotorula glutinis 5-formyluracil + succinate + CO2 5-formyluracil reacts subsequently to 5-carboxyuracil ?
1.14.11.6 thymine + 2-oxoglutarate + O2
-
 Rhodotorula glutinis 5-hydroxymethyluracil + succinate + CO2 5-hydroxymethyluracil reacts subsequently to 5-formyluracil ?