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Literature summary extracted from

  • Lontoh, S.; DiSpirito, A.A.; Semrau, J.D.
    Dichloromethane and trichloroethylene inhibition of methane oxidation by the membrane-associated methane monooxygenase of Methylosinus trichosporium OB3b (1999), Arch. Microbiol., 171, 301-308.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.25 Acetylene pMMO Methylosinus trichosporium
1.14.13.25 Dichloromethane competitively in presence of formate Methylosinus trichosporium
1.14.13.25 additional information different chlorinated hydrocarbons cause different inhibition patterns Methylosinus trichosporium
1.14.13.25 trichlorethylene non-competitively; pMMO Methylosinus trichosporium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.13.25 additional information
-
 additional information
-
 Methylosinus trichosporium

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.25 membrane membrane-bound particulate enzyme form termed pMMO Methylosinus trichosporium 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.25 formate + NAD(P)H + O2 Methylosinus trichosporium assay with whole cells ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.25 Methylosinus trichosporium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.25 formate + NAD(P)H + O2 assay with whole cells Methylosinus trichosporium ?
-
 ?
1.14.13.25 methane + NAD(P)H + O2
-
 Methylosinus trichosporium methanol + NAD(P)+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.25 MMO
-
 Methylosinus trichosporium
1.14.13.25 pMMO particulate, membrane-bound enzyme form Methylosinus trichosporium
1.14.13.25 sMMO soluble, cytoplasmic enzyme form Methylosinus trichosporium

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.25 NADH
-
 Methylosinus trichosporium