BRENDA - Enzyme Database

Substrate specificity of soluble methane monooxygenase. Mechanistic implications

Green, J.; Dalton, H.; J. Biol. Chem. 264, 17698-17703 (1989)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.13.25
cytoplasm
-
Methylococcus capsulatus
5737
-
Organism
EC Number
Organism
UniProt
Commentary
Textmining
1.14.13.25
Methylococcus capsulatus
-
Bath
-
1.14.13.25
Methylococcus capsulatus Bath
-
Bath
-
Reaction
EC Number
Reaction
Commentary
Organism
Reaction ID
1.14.13.25
methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O
mechanism
Methylococcus capsulatus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1.14.13.25
2,3-dimethylpentane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
3,4-dimethylpentan-2-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
2-methylpropane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
2-methylpropan-2-ol + 2-methylpropan-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
adamantane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-adamantanol + 2-adamantanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
beta-pinene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol + beta-pinene oxide + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
cis-1,3-dimethylcyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
3,5-dimethylcyclohexanol + 1-cis-3-dimethylcyclohexanol + NAD(P)+ + H2O + 1-trans-3-dimethylcyclohexanol
1-trans-3-dimethylcyclohexanol is produced in a low concentration
438937
Methylococcus capsulatus
?
1.14.13.25
cis-1,4-dimethylcyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-cis-4-dimethylcyclohexanol + NAD(P)+ + H2O + trans-2,5-dimethylcyclohexanol
trans-2,5-dimethylcyclohexanol is produced in a low concentration
438937
Methylococcus capsulatus
?
1.14.13.25
cis-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
cis-2,3-epoxybutane + cis-2-buten-1-ol + 2-butanone + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
cis-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
cis-2,3-epoxybutane + cis-2-buten-1-ol + 2-butanone + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?
1.14.13.25
heptane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-heptanol + 2-heptanol + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
hexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-hexanol + 2-hexanol + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
methane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
methanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
methane + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
methanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?
1.14.13.25
methylene cyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-cyclohexane-1-methanol + methylene cyclohexane oxide + 4-hydroxymethylene cyclohexane + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
additional information
broad specificity
438937
Methylococcus capsulatus
?
-
-
-
?
1.14.13.25
additional information
broad specificity
438937
Methylococcus capsulatus Bath
?
-
-
-
?
1.14.13.25
pentane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-pentanol + 2-pentanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
styrene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
styrene epoxide + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
styrene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
styrene epoxide + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
trans-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
trans-2,3-epoxybutane + trans-2-buten-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
trans-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
trans-2,3-epoxybutane + trans-2-buten-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.14.13.25
NADH
-
Methylococcus capsulatus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.14.13.25
NADH
-
Methylococcus capsulatus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.13.25
cytoplasm
-
Methylococcus capsulatus
5737
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1.14.13.25
2,3-dimethylpentane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
3,4-dimethylpentan-2-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
2-methylpropane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
2-methylpropan-2-ol + 2-methylpropan-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
adamantane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-adamantanol + 2-adamantanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
beta-pinene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol + beta-pinene oxide + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
cis-1,3-dimethylcyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
3,5-dimethylcyclohexanol + 1-cis-3-dimethylcyclohexanol + NAD(P)+ + H2O + 1-trans-3-dimethylcyclohexanol
1-trans-3-dimethylcyclohexanol is produced in a low concentration
438937
Methylococcus capsulatus
?
1.14.13.25
cis-1,4-dimethylcyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-cis-4-dimethylcyclohexanol + NAD(P)+ + H2O + trans-2,5-dimethylcyclohexanol
trans-2,5-dimethylcyclohexanol is produced in a low concentration
438937
Methylococcus capsulatus
?
1.14.13.25
cis-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
cis-2,3-epoxybutane + cis-2-buten-1-ol + 2-butanone + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
cis-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
cis-2,3-epoxybutane + cis-2-buten-1-ol + 2-butanone + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?
1.14.13.25
heptane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-heptanol + 2-heptanol + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
hexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-hexanol + 2-hexanol + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
methane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
methanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
methane + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
methanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?
1.14.13.25
methylene cyclohexane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-cyclohexane-1-methanol + methylene cyclohexane oxide + 4-hydroxymethylene cyclohexane + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
additional information
broad specificity
438937
Methylococcus capsulatus
?
-
-
-
?
1.14.13.25
additional information
broad specificity
438937
Methylococcus capsulatus Bath
?
-
-
-
?
1.14.13.25
pentane + NAD(P)H + O2
-
438937
Methylococcus capsulatus
1-pentanol + 2-pentanol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
styrene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
styrene epoxide + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
styrene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
styrene epoxide + NAD(P)+ + H2O
-
-
-
?
1.14.13.25
trans-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus
trans-2,3-epoxybutane + trans-2-buten-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus
?
1.14.13.25
trans-2-butene + NAD(P)H + O2
-
438937
Methylococcus capsulatus Bath
trans-2,3-epoxybutane + trans-2-buten-1-ol + NAD(P)+ + H2O
-
438937
Methylococcus capsulatus Bath
?