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Literature summary extracted from

  • Koop, D.R.
    Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a (1986), Mol. Pharmacol., 29, 399-404.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.29 4-nitrophenol substrate inhibition above 0.1 mM Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.29 microsome
-
 Oryctolagus cuniculus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.29 Oryctolagus cuniculus
-
 New Zealand white male rabbit
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.13.29
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.29 liver
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.29 4-nitrophenol + NADH + O2
-
 Oryctolagus cuniculus 4-nitrocatechol + NAD+ + H2O
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.14.13.29 0.127
-
 4-nitrophenol reconstituted system of purified isozyme 3a, dilaroylglyceryl-3-phosphorylcholine and NADPH-cytochrome P-450 reductase at pH 7.6 Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.13.29 6.8
-
 crude enzyme extract Oryctolagus cuniculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.29 NADH
-
 Oryctolagus cuniculus