EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.9 | 4-hydroxyphenylacetate | substrate inhibition by concentrations greater than 0.1 mM | Pseudomonas putida |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.9 | Pseudomonas putida | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O | dehydration of the C4a-hydroxyflavin is the rate-determining step in catalysis | Pseudomonas putida |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.9 | 2,4-dihydroxybenzoate | - |
Pseudomonas putida | ? | - |
? | |
1.14.14.9 | 3-(4-hydroxyphenyl)propionate + ? | - |
Pseudomonas putida | 3-(3,4-dihydroxy)phenylpropionate + ? | - |
? | |
1.14.14.9 | 4-aminobenzoate + ? | - |
Pseudomonas putida | 4-amino-3-hydroxybenzoate + ? | - |
? | |
1.14.14.9 | 4-aminophenylacetate + ? | - |
Pseudomonas putida | 4-amino-3-hydroxyphenylacetate + ? | - |
? | |
1.14.14.9 | 4-hydroxyphenylacetate + NADH + O2 | - |
Pseudomonas putida | 3,4-dihydroxyphenylacetate + NAD+ + H2O | - |
? | |
1.14.14.9 | additional information | substrates become hydroxylated at a position ortho to the hydroxyl group, 4-chlorophenylacetate, 4-fluorobenzoate and benzoate are not hydroxylated | Pseudomonas putida | ? | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.14.9 | 0.833 | - |
4-hydroxyphenylacetate | - |
Pseudomonas putida |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.9 | NADH | - |
Pseudomonas putida |