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Literature summary extracted from

  • Rao, P.V.S.; Sreeleela, N.S.; Premakumar, R.; Vaidyanathan, C.S.
    Regulation of the pathway for the degradation of anthranilate in Aspergillus niger (1971), J. Bacteriol., 107, 100-105.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.13.35 3-Hydroxyanthranilate induces Aspergillus niger
1.14.13.35 anthranilate induces, the enzyme activity increases with an increase in the concentration of anthranilate in the growth medium, optimal amounts of the enzyme are synthesized when the concentration of anthranilate is 1 mg/ml, further increase in the concentration results in a considerable decrease in the growth of the organism as well in the enzyme activity Aspergillus niger
1.14.13.35 kynurenine induces Aspergillus niger
1.14.13.35 L-tryptophan induces Aspergillus niger

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.35 cycloheximide inhibits the enzyme induction Aspergillus niger

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.35 Aspergillus niger
-
inducible enzyme
-
1.14.13.35 Aspergillus niger
-
UBC 814
-
1.14.13.35 Aspergillus niger UBC 814
-
UBC 814
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.13.35 0.0026
-
organism grown on the standard medium with kynurenine Aspergillus niger
1.14.13.35 0.0032
-
organism grown on the standard medium with tryptophan Aspergillus niger
1.14.13.35 0.0056
-
organism grown on the standard medium with 3-hydroxyanthranilate Aspergillus niger
1.14.13.35 0.0058
-
organism grown on the standard medium with anthranilate Aspergillus niger

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.35 anthranilate + NADPH + O2
-
Aspergillus niger 2,3-dihydroxybenzoate + NADP+ + NH3
-
?
1.14.13.35 anthranilate + NADPH + O2
-
Aspergillus niger UBC 814 2,3-dihydroxybenzoate + NADP+ + NH3
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.13.35 6
-
for optimal induction Aspergillus niger
1.14.13.35 8.2
-
assay at Aspergillus niger

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.35 NADPH
-
Aspergillus niger