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Literature summary extracted from

  • Yamashita, M.; Minato, S.; Arai, M.; Kishida, Y.; Nagatsu, T.; Umezawa, H.
    Purification of phenylalanine hydroxylase from human adult and foetal livers with a monoclonal antibody (1985), Biochem. Biophys. Res. Commun., 133, 202-207.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.16.1 49000
-
 x * 49000, adult liver enzyme, SDS-PAGE Homo sapiens
1.14.16.1 49000
-
 x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE Homo sapiens
1.14.16.1 52000
-
 x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE Homo sapiens
1.14.16.1 150000
-
 adult liver enzyme, gel filtration Homo sapiens
1.14.16.1 160000
-
 fetal liver enzyme, gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.16.1 adult and fetal liver enzyme, monoclonal antibody affinity chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.16.1 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.16.1 1.6
-
 fetal liver enzyme Homo sapiens
1.14.16.1 1.76
-
 adult liver enzyme Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.1 L-phenylalanine + tetrahydrobiopterin + O2
-
 Homo sapiens L-tyrosine + dihydrobiopterin + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.16.1 ? x * 49000, adult liver enzyme, SDS-PAGE Homo sapiens
1.14.16.1 ? x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.16.1 tetrahydrobiopterin
-
 Homo sapiens