Any feedback?
Literature summary extracted from
- Comparative study of biochemical parameters and kinetic properties of dopamine-beta-hydroxylase activity from cat and rat adrenals (1993), Comp. Biochem. Physiol. B, 104, 567-575.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.14.17.1 | 0.6 | - |
ascorbate | in the absence of Cu2+ | Felis catus |  |
| 1.14.17.1 | 1 | - |
ascorbate | in the presence of Cu2+ | Felis catus | |
| 1.14.17.1 | 1.1 | - |
ascorbate | - |
Rattus norvegicus | |
| 1.14.17.1 | 1.1 | - |
ascorbate | with or without Cu2+ | Felis catus | |
| 1.14.17.1 | 2 | - |
tyramine | - |
Felis catus | |
| 1.14.17.1 | 2.3 | - |
tyramine | - |
Rattus norvegicus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.17.1 | Cu2+ | enzyme not activated by exogenous copper but activity decreases at high concentrations | Rattus norvegicus | |
| 1.14.17.1 | Cu2+ | enzyme not activated by exogenous copper but activity decreases at high concentrations | Felis catus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.17.1 | Felis catus | - |
- |
- |
| 1.14.17.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.14.17.1 | additional information | - |
activity in the cat is twofold higher compared to rat | Rattus norvegicus |
| 1.14.17.1 | additional information | - |
activity in the cat is twofold higher compared to rat | Felis catus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.17.1 | 3,4-dihydroxyphenethylamine + ascorbate + O2 | - |
Rattus norvegicus | noradrenaline + dehydroascorbate + H2O | norepinephrine | ? | |
| 1.14.17.1 | tyramine + ascorbate + O2 | - |
Rattus norvegicus | octopamine + dehydroascorbate + H2O | - |
? | |
| 1.14.17.1 | tyramine + ascorbate + O2 | - |
Felis catus | octopamine + dehydroascorbate + H2O | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.17.1 | 4.6 | - |
- |
Rattus norvegicus |
| 1.14.17.1 | 4.8 | 5 | - |
Felis catus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
