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Literature summary extracted from

  • Bradbury, A.F.; Smyth, D.G.
    C-Terminal amide formation in peptide hormones (1985), Biogenetics of Neurohormonal Peptides (Hakanson, R. , Thorell, J. , eds) Academic Press, London, 171-186.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.17.3 peptidylglycine + ascorbate + O2 Bos taurus
-
 peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.17.3 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.17.3 pituitary gland
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.17.3 dansyl-D-Tyr-Val-Gly + ascorbate + O2
-
 Bos taurus dansyl-D-Tyr-Val-2-hydroxyglycine + dehydroascorbate + H2O
-
 ?
1.14.17.3 N-dansyl-L-Tyr-L-Val-Gly + ascorbate + O2
-
 Bos taurus N-dansyl-L-Tyr-L-Val-2-hydroxyglycine + dehydroascorbate + H2O
-
 r
1.14.17.3 peptidylglycine + ascorbate + O2
-
 Bos taurus peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O
-
 ?
1.14.17.3 peptidylglycine + ascorbate + O2 COOH-terminal glycine Bos taurus peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.14.17.3 0.143
-
 N-dansyl-L-Tyr-L-Val-Gly
-
 Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.17.3 8.5
-
-
 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.17.3 ascorbate dependent on Bos taurus