Literature summary extracted from

Chuang, L.T.; Thurmond, J.M.; Liu, J.W.; Kirchner, S.J.; Mukerji, P.; Bray, T.M.; Huang, Y.S.
Effect of conjugated linoleic acid on fungal DELTA6-desaturase activity in a transformed yeast system (2001), Lipids, 36, 139-143.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.14.19.3	Saccharomyces cerevisiae transformed with fungal DELTA6-desaturase gene	Mortierella alpina

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.19.3	conjugated linoleic acid	all CLA isomers inhibits significantly the activity of DELTA6-desaturase, the c9,t11 isomer is the most potent inhibitor	Mortierella alpina

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.19.3	linoleic acid + AH2 + O2	Mortierella alpina	-	gamma-linolenic acid + A + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.19.3	Mortierella alpina	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.19.3	linoleic acid + AH2 + O2	-	Mortierella alpina	gamma-linolenic acid + A + H2O	-	?
1.14.19.3	octadeca-9,12-dienoic acid + AH2 + O2	-	Mortierella alpina	gamma-linolenic acid + A + H2O	-	?

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Release 2023.1 (January 2023)