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Literature summary extracted from

  • Friedman, Y.; Lang, M.; Burke, G.
    Further characterization of bovine thyroid prostaglandin synthase (1975), Biochim. Biophys. Acta, 397, 331-341.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.99.1 thyrotropin tissue-specific stimulation in thyroid Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.99.1 Eicosa-5,8,11,14-tetraynoic acid
-
 Bos taurus
1.14.99.1 indomethacin
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.99.1 0.16
-
 arachidonic acid
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.99.1 cytoplasmic membrane probably associated with Bos taurus
-
-
1.14.99.1 microsome
-
 Bos taurus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.1 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.99.1 thyroid gland
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.1 arachidonic acid + AH2 + 2 O2
-
 Bos taurus prostaglandin E2 + A + H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.14.99.1 37
-
-
 Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.99.1 7 7.3 formation of prostaglandin E2 from arachidonic acid Bos taurus