Literature summary extracted from

Andrus, L.; Szabo, P.; Grady, R.W.; Hanauske, A.R.; Huima-Byron, T.; Slowinska, B.; Zagulska, S.; Hanauske-Abel, H.M.
Antiretroviral effects of deoxyhypusyl hydroxylase inhibitors. A hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1) (1998), Biochem. Pharmacol., 55, 1807-1818.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.99.29	deferiprone	0.2 mM in cells	Homo sapiens
1.14.99.29	mimosine	0.2 mM in cells	Homo sapiens

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.99.29	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.99.29	T-lymphocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.99.29	N'-(4-aminobutyl)lysine + electron donor + O2	i.e. deoxyhypusine	Homo sapiens	N'-(4-amino-2-hydroxybutyl)lysine + oxidized electron donor + H2O	i.e. hypusine	?

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Release 2023.1 (January 2023)