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Literature summary extracted from

  • Cornejo, J.; Beale, S.I.
    Algal heme oxygenase from Cyanidium caldarium. Partial purification and fractionation into three required protein components (1988), J. Biol. Chem., 263, 11915-11921.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.14.18 Fe/S cluster heme oxygenase consists of 3 required protein components: a ferredoxin-like Fe-S cluster protein that can be replaced by ferredoxin, a protein that is inactivated by diethyldicarbonate, inactivation is blocked by heme, a protein with ferredoxin-linked cytochrome c reductase activity Cyanidium caldarium

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.18 Sn-protoporphyrin 0.002 mM, 80% inhibition Cyanidium caldarium

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.18 soluble
-
 Cyanidium caldarium
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.14.18 Iron heme oxygenase consists of 3 required protein components: a ferredoxin-like Fe-S cluster protein that can be replaced by ferredoxin, a protein that is inactivated by diethyldicarbonate, inactivation is blocked by heme, a protein with ferredoxin-linked cytochrome c reductase activity Cyanidium caldarium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.14.18 additional information
-
 heme oxygenase consists of 3 components: a 22000 Da ferredoxin-like Fe/S cluster protein that can be replaced by ferredoxin, a 38000 Da protein that is inactivated by diethyldicarbonate, inactivation is blocked by heme, a 37000 Da protein with ferredoxin-linked cytochrome c reductase activity Cyanidium caldarium

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.18 Cyanidium caldarium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.14.18 partial Cyanidium caldarium

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.18 heme + electron donor + O2 algal heme oxygenase requires a second reductant in addition to reduced pyridine nucleotide Cyanidium caldarium biliverdin + Fe2+ + CO + oxidized eletron donor + H2O
-
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