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Literature summary extracted from

  • Holdom, M.D.; Hay, R.J.; Hamilton, A.J.
    The Cu,Zn superoxide dismutases of Aspergillus flavus, Aspergillus niger, Aspergillus nidulans, and Aspergillus terreus: purification and biochemical comparison with the Aspergillus fumigatus Cu,Zn superoxide dismutase (1996), Infect. Immun., 64, 3326-3332.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.15.1.1 CN-
-
 Aspergillus flavus
1.15.1.1 CN-
-
 Aspergillus nidulans
1.15.1.1 CN-
-
 Aspergillus niger
1.15.1.1 CN-
-
 Aspergillus terreus
1.15.1.1 diethyldithiocarbamate
-
 Aspergillus flavus
1.15.1.1 diethyldithiocarbamate
-
 Aspergillus nidulans
1.15.1.1 diethyldithiocarbamate
-
 Aspergillus niger
1.15.1.1 diethyldithiocarbamate
-
 Aspergillus terreus
1.15.1.1 EDTA
-
 Aspergillus flavus
1.15.1.1 EDTA
-
 Aspergillus nidulans
1.15.1.1 EDTA
-
 Aspergillus niger
1.15.1.1 EDTA
-
 Aspergillus terreus
1.15.1.1 N3-
-
 Aspergillus flavus
1.15.1.1 N3-
-
 Aspergillus nidulans
1.15.1.1 N3-
-
 Aspergillus niger
1.15.1.1 N3-
-
 Aspergillus terreus
1.15.1.1 o-phenanthroline
-
 Aspergillus flavus
1.15.1.1 o-phenanthroline
-
 Aspergillus nidulans
1.15.1.1 o-phenanthroline
-
 Aspergillus niger
1.15.1.1 o-phenanthroline
-
 Aspergillus terreus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.15.1.1 Cu2+
-
 Aspergillus nidulans
1.15.1.1 Cu2+
-
 Aspergillus niger
1.15.1.1 Cu2+
-
 Aspergillus flavus
1.15.1.1 Cu2+
-
 Aspergillus terreus
1.15.1.1 Zn2+
-
 Aspergillus nidulans
1.15.1.1 Zn2+
-
 Aspergillus niger
1.15.1.1 Zn2+
-
 Aspergillus flavus
1.15.1.1 Zn2+
-
 Aspergillus terreus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.15.1.1 18000
-
 x * 18000, Cu,Zn-SOD, SDS-PAGE Aspergillus niger
1.15.1.1 19250
-
 x * 19250, Cu,Zn-SOD, SDS-PAGE Aspergillus nidulans
1.15.1.1 55000
-
 Cu,Zn-SOD, gel filtration Aspergillus nidulans
1.15.1.1 68500
-
 Cu,Zn-SOD, gel filtration Aspergillus terreus
1.15.1.1 69000
-
 Cu,Zn-SOD, gel filtration Aspergillus niger
1.15.1.1 123000
-
 Cu,Zn-SOD, gel filtration Aspergillus flavus
1.15.1.1 175000
-
 x * 175000, Cu,Zn-SOD, SDS-PAGE Aspergillus terreus
1.15.1.1 185000
-
 x * 185000, Cu,Zn-SOD, SDS-PAGE Aspergillus flavus

Organism

EC Number Organism UniProt Comment Textmining
1.15.1.1 Aspergillus flavus
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus flavus CuZn-SOD
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus nidulans
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus nidulans CuZn-SOD
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus niger
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus niger CuZn-SOD
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus terreus
-
 Cu,Zn-SOD
-
1.15.1.1 Aspergillus terreus CuZn-SOD
-
 Cu,Zn-SOD
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.15.1.1 Cu,Zn-SOD Aspergillus nidulans
1.15.1.1 Cu,Zn-SOD Aspergillus niger
1.15.1.1 Cu,Zn-SOD Aspergillus flavus
1.15.1.1 Cu,Zn-SOD Aspergillus terreus

Reaction

EC Number Reaction Comment Organism Reaction ID
1.15.1.1 2 superoxide + 2 H+ = O2 + H2O2 amino acid composition, comparison Aspergillus nidulans
a
1.15.1.1 2 superoxide + 2 H+ = O2 + H2O2 amino acid composition, comparison Aspergillus niger
a
1.15.1.1 2 superoxide + 2 H+ = O2 + H2O2 amino acid composition, comparison Aspergillus flavus
a
1.15.1.1 2 superoxide + 2 H+ = O2 + H2O2 amino acid composition, comparison Aspergillus terreus
a

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.15.1.1 additional information
-
-
 Aspergillus nidulans
1.15.1.1 additional information
-
-
 Aspergillus niger
1.15.1.1 additional information
-
-
 Aspergillus flavus
1.15.1.1 additional information
-
-
 Aspergillus terreus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.15.1.1 O2- + H+
-
 Aspergillus nidulans O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus niger O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus flavus O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus terreus O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus niger CuZn-SOD O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus nidulans CuZn-SOD O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus flavus CuZn-SOD O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Aspergillus terreus CuZn-SOD O2 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.15.1.1 ? x * 19250, Cu,Zn-SOD, SDS-PAGE Aspergillus nidulans
1.15.1.1 ? x * 175000, Cu,Zn-SOD, SDS-PAGE Aspergillus terreus
1.15.1.1 ? x * 185000, Cu,Zn-SOD, SDS-PAGE Aspergillus flavus
1.15.1.1 ? x * 18000, Cu,Zn-SOD, SDS-PAGE Aspergillus niger

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.15.1.1 50
-
 1 h, stable Aspergillus nidulans
1.15.1.1 50
-
 1 h, stable Aspergillus niger
1.15.1.1 50
-
 1 h, stable Aspergillus flavus
1.15.1.1 50
-
 1 h, stable Aspergillus terreus
1.15.1.1 70
-
 loss of activity after 30 min, Cu,Zn-SOD Aspergillus nidulans
1.15.1.1 70
-
 loss of activity after 30 min, Cu,Zn-SOD Aspergillus niger
1.15.1.1 70
-
 loss of activity after 30 min, Cu,Zn-SOD Aspergillus flavus
1.15.1.1 70
-
 loss of activity after 30 min, Cu,Zn-SOD Aspergillus terreus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.15.1.1 7 11
-
 Aspergillus nidulans
1.15.1.1 7 11
-
 Aspergillus niger
1.15.1.1 7 11
-
 Aspergillus flavus
1.15.1.1 7 11
-
 Aspergillus terreus