Literature summary extracted from

Nunez, A.; Castillo, M.; Iglesias, J.; Martinez-Cayuela, M.; Gonzales-Pacanowska, D.; Garcia-Peregrin, E.
Regulation of mevalonate 5-pyrophosphate decarboxylase in HeLa cells. Inhibition of enzymatic protein synthesis by serum lipoproteins (1997), Int. J. Biochem. Cell Biol., 29, 1037-1041.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.1.1.33	ATP + 5-diphosphomevalonate	Homo sapiens	the enzyme is responsible for regulation of cholesterogenesis. Response to lipoprotein content of culture medium	ADP + phosphate + isopentenyl diphosphate + CO2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.33	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.1.1.33	HeLa cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.33	ATP + 5-diphosphomevalonate	-	Homo sapiens	ADP + phosphate + isopentenyl diphosphate + CO2	-	?
4.1.1.33	ATP + 5-diphosphomevalonate	the enzyme is responsible for regulation of cholesterogenesis. Response to lipoprotein content of culture medium	Homo sapiens	ADP + phosphate + isopentenyl diphosphate + CO2	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)