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Literature summary extracted from

  • Wagner, U.G.; Werber, M.M.; Beck, Y.; Hartman, J.R.; Frolow, F.; Sussman, J.L.
    Characterization of crystals of genetically engineered human manganese superoxide dismutase (1989), J. Mol. Biol., 206, 787-788.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.15.1.1 medicine potential target for drug design Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.15.1.1 Mn-SOD, expression in Escherichia coli Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.15.1.1 from recombinant Mn-SOD, asymmetric unit, hanging drop technique, room temperature, equilibration of 3-4 mg/ml enzyme in ammonium phosphate, pH 5.9, plus 10% 2-methyl-2,4-pentanediol against 32% 2-methyl-2,4-pentanediol, X-ray analysis Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.15.1.1 22000
-
 x * 22000, amino acid sequence determination Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.15.1.1 Homo sapiens
-
 Mn-SOD
-
1.15.1.1 Homo sapiens Mn-SOD
-
 Mn-SOD
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.15.1.1 O2- + H+
-
 Homo sapiens O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Homo sapiens Mn-SOD O2 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.15.1.1 ? x * 22000, amino acid sequence determination Homo sapiens